Prof. Shlomo Nir

Education:

1962 - B.Sc. in from The Hebrew University of Jerusalem.
1965 - M.Sc. in Theoretical Physics from The Hebrew University of Jerusalem.
1969 - Ph.D. in Theoretical Physics from The Hebrew University of Jerusalem.

Research Interests:

Water purification from organic and inorganic contaminants and microorganisms by micelle-clay and organo-clay complexes. Cation adsorption to clay particles and membranes. Preparation of herbicide formulations based on organo-clays and micelle-clay, which reduce herbicide leaching, volatilization and photodegradation. Particle aggregation in bulk and on surfaces. Membrane fusion: Vesicle-vesicle, virus-vesicle and virus-cell. Interactions of peptides with membranes and pore formation. Endocytosis.

 

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Publications

Publications

A. Nennemann, Y. Mishael, S. Nir, B. Rubin, T. Polubesova, F. Bergaya, H. van Damme and G. Lagaly. 2001Clay-Based Formulations of Metolachlor with Reduced LeachingAppl. Clay Sci. 18, 265-275.

K. Yusim, S. Nir and N. Lahav. 2001A Model for Proto-tRNA LoadingJ. Theor. Biol. 208, 109-116.

S. Assouline, S. Nir and N. Lahav.2001Simulation of Non-Enzymatic Template-Directed Synthesis of Oligonucleotides and PeptidesJ. Theor. Biol. 208, 117-125.

M.T. Girao da Cruz, S. Simoes, P.P.C. Pires, S. Nir and M.C. Pedroso de Lima. 2001Kinetic Analysis of the Initial Steps Involved in Lipoplex-Cell Interactions: Effect of Various Factors that Influence Transfection Activity. Biochem. Biophys. Acta 1510, 136-151.

N. Lahav, S. Nir and A.C. Elitzur. 2001The Emergence of Life on Earth. Prog. In Biophys. and Mol. Biol. 75,75-120.

T. Polubesova, S. Nir, O. Rabinovitz and B. Rubin. 2001Mepiquat-Acetochlor Formulations: Sorption and Leaching. Applied Clay Science 18, 299-307.

Y. El-Nahhal, T.Undabeytia, T. Polubesova, Y.G. Mishael, S. Nir, and B. Rubin. 2001Organo-Clay Formulations of Pesticides: Reduced Leaching and Photodegradation. Applied Clay Sci. 18, 309-326.

Y. El-Nahhal, S. Nir, C. Serban, O. Rabinovitz, and B. Rubin. 2001Organo-Clay Formulation of Acetochlor for Reduced Movement in Soil. J. Agri. Food Chem. 49, 5364-5371.

S. Nir, G. Rytwo, T. Polubesova, T. Undabeytia, and C. Serban. 2002Adsorption of Organic Cations on Clays: Experimental Results and Modeling. In: Clay Complexes and Interactions. S. Yariv and H. Cross (eds.) Marcel Dekker Publ. 193-222.

M. Naim, S. Nir, A.I, Spielman, I. Peri, S. Rodin and M. Samuelov-Zubare. 2002The Hypothesis of Receptor-Dependent and Receptor-Independent Mechanisms for Bitter and Sweet Taste Transduction: Implications for Slow Taste Onset and Lingering Aftertaste. In: ACS Symposium on the Chemistry of Taste, Given, P. and Paredes, D. (eds.) Invited book chapter, American Chemical Society 2-17.

Y.G. Mishael, T. Undabeytia, G. Rytwo, B. Papahadjopoulos-Sternberg, B. Rubin, and S. Nir. 2002Sulfometuron Adsorption via Alkylammonium Cations Adsorption as Monomers and Micelles on Montmorillonite. J. Agri. Food Chem. 50, 2856-2863.

Y.G. Mishael, T. Undabeytia, O. Rabinovitz, B. Rubin and S. Nir. 2002Slow Release Formulations of Sulfometuron Incorporated in Micelles Adsorbed on Montmorillonite. J. Agri. Food Chem. 50, 2864-2869.

T. Polubesova, S.Nir, Z. Gerstl, M. Borisover, and B. Rubin. 2002Imazaquin Adsorbed on Pillared Clay and Crystal Violet-Montmorillonite Complexes for Reduced Leaching in Soil. J. Environ. Qual. 31, 1657-1664.

A. Saez-Cirion, S. Nir, M. Lorizate, A. Agirre, A. Cruz, J. Perez-Gil and J.L. Nieva. 2002Interaction of the HIV-1 gp41 Pretransmembrane Region with Viral Envelope-Type Lipids: Surface Aggregation and Membrane Perturbations Mediated by Sphingomyelin and Cholesterol. J. Biol. Chem. 277, 21776-21785.

T. Undabeytia, S. Nir, G. Rytwo, C. Serban, E. Morillo and C. Maqueda. 2002Modeling Adsorption-Desorption Processes of Cu on Edge and Planar Sites of Montmorillonite.Environ. Sci. Techn. 36, 2677-2683.

Y.G. Mishael, T. Undabeytia, O.Rabinovitz, B. Rubin, and S. Nir. 2003Sulfosulfuron Incorporation in Micelles Adsorbed on Montmorillonite for Slow Release Formulations. J. Agri. Food Chem. 51, 2553-2559.

T. Polubesova, S. Nir, O. Rabinovitz, M. Borisover and B. Rubin. 2003Sulfentrazone Adsorbed on Micelle-Montmorillonite Complexes for Slow Release in Soil. J. Agri. Food Chem. 51, 3410-3414.

T. Undabeytia, Y.G. Mishael, S. Nir, B. Papahadjopoulos-Sternberg, B. Rubin, E. Morillo and C. Maqueda. 2003. A Novel System for Reducing Leaching from Formulations of Anionic Herbicides: Clay-Liposomes. Environ. Sci. Techn. 37, 4475-4480.

M.J. Gomara, S. Nir and J.L. Nieva. 2003Effects of Sphingomyelin on Melittin Pore Formation. Biochim. Biophys. Acta 1612, 83-89.

J.L. Nieva, A. Agirre, S. Nir and L. Carrasco. 2003Mechanisms of Membrane Permeabilization by Poliovirus 2B Viroporin. FEBS Lett. 552, 68-73.

I. Nunes-Correa, S. Nir and M.C. Pedroso de Lima. 2003Kinetics of Influenza Virus Fusion with the Endosomal and Plasma Membranes of Cultured Cells. Effect of Temperature J. Membr. Biol. 195, 21-26.

R.E. Eliaz, S. Nir, C. Marty and F.C. Szoka, Jr. 2004Determination and Modeling of Kinetics of Cancel Cell Killing by Doxorubicin and Doxorubicin Encapsulated in Targeted Liposomes.Cancer Res. 64, 711-718.

G. Rytwo, M. Tavasi, S. Afuta, and S. Nir. 2004Adsorption of Difenzoquat on Montmorillonite: Model Calculations and Influence on the Hydrophobicity. Appl. Clay Sci. 24, 149-157.

D. Yaron-Marcovitch, S. Nir and Y. Chen. 2004Fluridone Adsorption-Desorption on Organo-Clays. Appl. Clay Sci. 24, 167-175.

T. Polubesova, M. Epstein, S. Yariv, I. Lapides, and S. Nir. 2004Adsorption of Alizarinate Organic Micelle Complexes on Na Montmorillonite. Appl. Clay Sci. 24, 177-183.

I. Nunes-Correa, A. Eulalio, S. Nir, and Maria C. Pedroso de Lima.2004Caveolae as an Additional Route for Influenza Virus Endocytosis in MDCK Cells. Cellular & Molecular Biology Letters 9, 47-60.

T. Undabeytia, S. Nir, and M.J. Gomara. 2004Clay-Liposome Interactions: Fluorescence Measurements and Structural Implications for Slow Release Formulations on Herbicides.Environ. Sci. Technol. 20, 6605-6610.

D. Yaron-Marcovitch, Y. Chen, S. Nir, and R. Prost. 2005High Resolution Electron Microscopy (HRTEM) Technol. 39, 1231-1238.

T. Polubesova, S. Nir, D. Zadaka, O. Rabinovitz, C. Serban, L. Groisman and B. Rubin. 2005Water Purification from Organic Contaminants by Optimized Micelle-Clay Systems. Environ. Sci. Technol. 39, 2343-2348.

D. Zadaka, T. Polubesova, Y.G. Mishael, A. Spitzy, H. Koehler, E. Wakshal, O. Rabinovitz and S. Nir. 2005Determination of Release of Organic from Micelle-Clay Complexes and their Re-Adsorption in Sand/Clay Columns. Applied Clay Sci. 29, 282-286.

T. Polubesova, D.Zadaka, L. Groisman and S. Nir. 2006Water Remediation by Micelle-Clay System: Case Study for Antibiotics. Water Res. 40, 2369-2374.

S. Nir, Y. El-Nahhal, T. Undabeytia, G. Rytwo, T. Polubesova, Y. Mishael, O. Rabinovitz and B. Rubin. 2006Clays and Pesticides. In: Handbook of Clay Science. F. Bergaya, B.K.G. Theng and G. Lagaly (eds.) pp. 677-691. Elsevier Science Publisher.

D. Zadaka, Y.G. Mishael, T. Polubesova, C. Serban and S. Nir. 2007 Modified Silicates and Porous Glass as Adsorbents for Removal of Organic Pollutants from Water and Comparison with Activated Carbon. Appl.Clay Sci.36, 174-181.

T. Undabeytia, S. Nir, T. Sanchez-Verdejo, J. Villaverde, C. Maqueda and E. Morillo. 2008A clay-vesicle system for water purification from organic pollutants. Water Research.42, 1211-1219.

T. Sanchez-Verdejo, T. Undabeytia, S. Nir, C. Maqueda and E. Morillo. 2008Environmentally friendly slow release formulations of alachlor based on clay-phosphatidylcholine. Environ. Sci. Technol.42, 5779-5784.

T. Sanchez-Verdejo, T. Undabeytia, S. Nir, J. Villaverde, C. Maqueda and E. Morillo. 2008.Environmentally friendly formulations of alachlor and atrazine: preparation, characterization, and reduced leaching. Journal of Agricultural and Food Chemistry.56, 10192-10199.

A. Agirre, M. Lorizate, S. Nir, S. and J.L. Nieva. 2008Poliovirus 2B insertion into lipid monolayers and pore formation in vesicles modulated by anionic phospholipids. Biochim. Biophys. Acta. 1778, 2621-2626.

J.L. Nieva, N. Huarte, S. Nir, D. Weliky. Induced Perturbations and Adopted Conformations in Membranes by the HIV-1 Fusion Peptide. In: "Membrane-active peptides: methods and results on structure and function" (M. Castanho ed.) IUL (International University Line) Publishers, La Jolla, California, USA.(in press).

D. Zadaka , S. Nir , Y. Mishael, A. Radian. Atrazine removal from water by olycation-clay composites: Effect of dissolved organic matter and comparison to activated carbon. Water Research (in press).

Books

S. Shoval and S. Nir. (Editors) 2003Special Issue, Third Mediterranean Clay Meeting. Applied Clay Sci. 24.

Patents

S. Nir, B. Rubin, Y. Mishael, T. Undabeytia, O. Rabinovitch and T. Polubesova. 2003Controlled Release Formulations of Anionic Herbicides. WO 02/052939 A1.